https://lifesciencejournal.pk/index.php/lsjp/issue/feed Life Science Journal of Pakistan 2020-07-11T17:23:00-04:00 Yasar Saleem lifesciencejournals@gmail.com Open Journal Systems <p>Life Science Journal of Pakistan (LSJP) is an open-access peer-review journal that is published quarterly. Journal is free and there is no fee for processing or publishing of manuscripts. The journal publishes original articles, review articles, letters to editors, case reports, or short communications technical notes and perspectives. LSJP provides immediate open access to its content so that making research freely available to the public supports a greater global exchange of knowledge which is essential to promote research in the life science domain. The journal publishes contents related to the biology of living things. It may include subjects from biochemistry, microbiology, zoology, plant science, agriculture science, biotechnology, molecular biology, medical sciences, epidemiology, and food science. </p> https://lifesciencejournal.pk/index.php/lsjp/article/view/42 Editorial Issue 1 Volume 2 2020-07-11T16:49:59-04:00 Yasar Saleem ysaleem73@hotmail.com <p align="justify">This is great pleasure and honor for me that Life Science Journal of Pakistan (LSJP) is publishing its third issue in days of COVID-19 Pandemic partial Lockdown. This global pandemic has changed almost all walks of life but for biological scientists, COVID has launched a new challenge of developing its treatment, cure, patient management, controlling mortality as well finding measures of preventing the spread of infection. The government’s agencies and health care professionals are trying their full efforts to mitigate this worst disease and scientists are trying to address this disease by working on vaccine development and finding new drugs for disease management. &nbsp;LSJP team extends its best wishes to all those working for the control, management, and treatment of this deadly disease and wishes to publish research and reviews regarding COVID-19 in the near future.</p> <p align="justify">LSJP covers different areas of life science encompassing, Biotechnology, Cell Biology, Medical and Allied Sciences, Plant Sciences, Microbiology, Molecular Biology, Biochemistry, and Animal Sciences. In Pakistan, we have a very limited number of recognized journals, due to which publication time is very long and one has to wait for a very long period to get the work published. LSJP was started to share the burden of pre-existing journals and publish the research articles in minimum possible time using the same standard procedure followed by most of the popular journals. There has been a great effort by our team, particularly the Journal manager, all section editors, chief editor, and chief executive.&nbsp; Team LSJP made every effort to make the process of manuscript submission, review and publication very user friendly and convenient, for that we used a similar model as that of journals of repute.</p> <p align="justify">In the third issue, four manuscripts will be published, in medical and allied fields, we have accepted a total of three manuscripts out of which two are original research articles and one is mini-review. While the fourth manuscript is related to plant sciences. In the former category, a very unique observation of needlestick injury during nursing practices was selected for publication. That manuscript provides insight regarding the safer delivery of an injection. This encompasses direct hospital experiences and will be helpful for paramedics. &nbsp;The second manuscript of this category explains the prevalence of HBV infection among pre-operative patients in remote areas of KPK, Pakistan. While a review has been accepted for publication that covers the role of PCBs and heavy metals on thyroid function and brain. &nbsp;We feel it will be helpful for relevant scientists and researchers at large to get the benefit of these articles. The last article accepted for publication covers morphological and other quality traits of oil crop sunflower based on <em>improved</em> oil contents, oil quality, and yield by using hybrids. This research may be used for the improvement of yield and other quality traits in breeding programs of sunflowers. LSJP will continue addressing scientific trends of life science-related all disciplines mentioned in the scope of LSJP, for that we hope more and active participation of scholars from academia and R&amp;D institutes.&nbsp;</p> <p align="&quot;justify”">In the end, I congratulate the LSJP team and I am thankful to all especially the Journal Manager for his hard work and sincere efforts to covert our dream of establishing a new journal into a reality. I am also thankful to Chief Executive, Chief Editor, Section Editors, and reviewers for their help and support for bringing LSJP at this level of starting its journey by taking the first step towards excellence in life sciences.</p> <p><strong>&nbsp;</strong></p> <p><strong>&nbsp;</strong><strong>&nbsp;</strong></p> <p><strong>Dr. Yasar Saleem,</strong></p> <p>Managing Editor,</p> <p>Life Science Journal of Pakistan</p> 2020-07-11T00:00:00-04:00 Copyright (c) 2020 Life Science Journal of Pakistan https://lifesciencejournal.pk/index.php/lsjp/article/view/25 Prevalence of needlestick injury and nursing practices regarding safe injection and sharp disposal while working in critical care settings of two tertiary care hospitals 2020-07-08T08:00:02-04:00 Shah Zeb just4szeb@gmail.com Tazeen Saeed Ali tazeen.ali@aku.edu <p>This observational cross-sectional study design (Pilot) was conducted to assess the prevalence of needle stick injury (NSI) and nursing practices regarding safe injection and sharp disposal in critical care units of two tertiary care hospitals from 1<sup>st</sup> July to 30<sup>th</sup> August 2014. Data was collected using a self-developed questionnaire about the prevalence of NSI and nurses’ pract­ices regarding safe injection and sharp disposal after a thorough literature review and then was given to the expert for review. Finally, the data was collected from the participants after verbal consent. The study result showing that about half of the nurses have no knowledge regarding the disposal of sharp and it has been found that 47.8% re-cap the needle before disposal. While 32.6% reported needle prick injury. The study concluded that inadequate knowledge among nurses about safe nursing practices and lack of using preventive measures from NSI were identified. Lack of reporting is also a factor identified in this study.</p> <p> </p> 2020-07-11T00:00:00-04:00 Copyright (c) 2020 Life Science Journal of Pakistan https://lifesciencejournal.pk/index.php/lsjp/article/view/24 Incidences of HBV infection among pre-operative patients of elective surgeries in Tehsil Dargai Malakand KPK, Pakistan 2020-07-08T07:54:32-04:00 Abd Ullah abdullah4us.71@gmail.com Attaullah abdullah4us.71@gmail.com Latif Ullah abdullah4us.71@gmail.com Faheem Anwar abdullah4us.71@gmail.com Misbahud Din abdullah4us.71@gmail.com Sikander Khan Sherwani sikander_biology@hotmail.com Munib Ahmad abdullah4us.71@gmail.com <p><strong>Background: </strong>Hepatitis is a deadly liver disease caused by the hepatitis virus (HBV) it is considered the 10th leading cause of death worldwide (WHO) and about 350 million people worldwide suffer from chronic HBV infection. Viral hepatitis is an infectious disease that can transmit from one individual to another individual through blood transfusion, parental routes, and contaminated body fluids like saliva, semen, and blood.</p> <p><strong>Methodology: </strong>In the present study the targeted patients were screened for HBV infection through ICT (Immune Chromatographic Technique) method and the ICT positive cases were confirmed through the ELISA technique. </p> <p><strong>Results: </strong>A total of 4500 patients were included in this study, out of which 110 cases were found positive for HBV infection. The frequency of Hepatitis B infection was 110 (1.8%) of the total population in the registered patients. The highest ratio of<strong> prevalence was found in the age group of 41-60 years (</strong>45%)<strong>. </strong>On gender-based study, the infection rate was found higher in males 75 (68.1%) as compared to females 35 (31.8%). The history of the patient's previous surgeries and disease records were also taken. The highest ratio of positivity was found 64 (58.1%) in patients having a blood transfusion in past, followed by previous surgeries 30 (27.2%), dental procedures 10 (9%) and Jaundice was present 6 (5.4%) in seropositive of HBV Patients</p> <p><strong>Conclusion:</strong> The prevalence of HBV infection is very high in hospitalized patients; it might be due to improper screening before surgery. The reason may be the use of non-sterilized surgical instruments, blood products, and lack of untrained staff.</p> 2020-07-11T00:00:00-04:00 Copyright (c) 2020 Life Science Journal of Pakistan https://lifesciencejournal.pk/index.php/lsjp/article/view/31 Combining ability studied for morphological and other quality traits of sunflower (Helianthus annuus L.) under line× tester fashion 2020-07-08T08:36:25-04:00 Habib ur Rehman mianhabib459@gmail.com Farooq Ahmad Khan farooq_pbg@yahoo.com Ahsan Iqbal ahsanuaf2003@yahoo.com Atif Naeem atifnaeempbg@gmail.com Muhammad Qasim javed mianhabib469@gmail.com <p>The objective of the present study was to check the improved oil contents, oil quality, and achene yield. The total number of five females’ lines (PBG-101, 102,103,104, and 105) were crossed with three testers (PBG-106, 107, and 108) to produce fifteen crosses. Female lines were crossed with male testers for the production of hybrids in the first season. Then these hybrids with their parents were sown in RCBD design by using three replications in the next coming season for checking their performance. Then combining ability (GCA and SCA) of different yield contributing traits (internodal length, leaf area, number of leaves plant-1, achene yield plant-1, and quality-related traits (oil contents, oleic acid, and linoleic acid) were checked. Among the lines, PBG-103 had shown the highly considerable GCA for leaf area and significant GCA for internodal length, PBG-105 had shown the highly considerable GCA for the leaf area, oil contents, and negative considerable GCA for linoleic acid. Among the testers, PBG-105 was shown the highly considerable GCA for internodal length and oil contents. Hybrid (PBG-104 × PBG-106) had shown the highly considerable SCA effects for the number of leaves plant-1, achene yield plant-1, and oleic acid. The highly significant results were shown by the crosses (PBG-105 × PBG-108, PBG-103 × PBG-107, PBG-102 × PBG-106) for oil contents. The cross PBG-103 × PBG-106 shown highly considerable with negative SCA for linoleic acid. These hybrids would be used for the improvement of yield and other quality traits in future breeding programs.</p> 2020-07-11T00:00:00-04:00 Copyright (c) 2020 Life Science Journal of Pakistan https://lifesciencejournal.pk/index.php/lsjp/article/view/41 List of Contents Issue 1 Volume 2 2020-07-11T03:53:34-04:00 Muhammad Shaheen Iqbal admin@lifesciencejournal.pk <p><strong>&nbsp;</strong></p> <p><strong>LIST OF CONTENTS </strong></p> <table width="717"> <tbody> <tr> <td width="58"> <p>S. No</p> </td> <td width="537"> <p>TITLE</p> </td> <td width="38"> <p>&nbsp;</p> </td> <td width="83"> <p>Page No.</p> </td> </tr> <tr> <td width="58"> <p>&nbsp;</p> </td> <td width="537"> <p>List of Contents</p> </td> <td width="38"> <p>&nbsp;</p> </td> <td width="83"> <p>ii</p> </td> </tr> <tr> <td width="58"> <p>&nbsp;</p> </td> <td width="537"> <p>Editorial</p> </td> <td width="38"> <p>&nbsp;</p> </td> <td width="83"> <p>iii</p> </td> </tr> <tr> <td width="58"> <p>01</p> </td> <td width="537"> <p><strong>Prevalence of needlestick injury and nursing practices regarding safe injection and sharp disposal while working in critical care settings of two tertiary care hospitals </strong></p> <p>*Shah Zeb1, Tazeen Saeed Ali2</p> </td> <td width="38"> <p>&nbsp;</p> </td> <td width="83"> <p>&nbsp;</p> <p>&nbsp;</p> <p>04-07</p> </td> </tr> <tr> <td width="58"> <p>02</p> </td> <td width="537"> <p><strong>Incidences of HBV infection among pre-operative patients of elective surgeries in Tehsil Dargai Malakand KPK, Pakistan </strong></p> <p>Abdullah 1*, Attaullah 2, Latif Ullah 3, Faheem Anwar 4, Misbahud Din 5, Sikander Khan Sherwani 6, Munib Ahmad 7</p> </td> <td width="38"> <p>&nbsp;</p> </td> <td width="83"> <p>08-13</p> </td> </tr> <tr> <td width="58"> <p>03</p> </td> <td width="537"> <p><strong>Combining ability studied for morphological and other quality traits of sunflower (<em>Helianthus annuus L.</em>) under line× tester fashion</strong></p> <p>Habib Ur Rehman1*, Farooq Ahmad Khan1, Ahsan Iqbal1, Atif Naeem1, Muhammad Qasim javed2.</p> </td> <td width="38"> <p>&nbsp;</p> </td> <td width="83"> <p>&nbsp;</p> <p>14-19</p> </td> </tr> <tr> <td width="58"> <p>04</p> </td> <td width="537"> <p><strong>Impact of Thyroid Hormones Disrupting Potential of Environmental Polychlorinated Biphenyls and Heavy Metals on Brain Functions: A Mini Review </strong></p> <p>*Abdul Qader Hayat1</p> </td> <td width="38"> <p>&nbsp;</p> </td> <td width="83"> <p>&nbsp;</p> <p>&nbsp;</p> <p>20-28</p> </td> </tr> </tbody> </table> <p><strong>&nbsp;</strong></p> <p><strong>&nbsp;</strong></p> 2020-07-11T00:00:00-04:00 Copyright (c) 2020 Life Science Journal of Pakistan https://lifesciencejournal.pk/index.php/lsjp/article/view/30 Impact of Thyroid Hormones Disrupting Potential of Environmental Polychlorinated Biphenyls and Heavy Metals on Brain Functions: A Review Article 2020-07-08T08:20:45-04:00 Abdul Qader Hayat Pharmacistqader316@gmail.com <p>The normal functions of the brain depend upon thyroid hormones including tetraiodothyronine and tri-iodothyronine. The environmental polychlorinated biphenyls produce neurological deficiencies by disturbing the normal cascade of thyroid hormones in the brain. These chemicals mimic the structure of thyroid hormones. Like thyroid hormones, these toxic compounds also contain a biphenyl ring and halogen atoms in their basic structure. These toxic environmental chemicals mostly act at receptor levels and have the ability to attach to thyroid hormones binding proteins. The disturbance created by these environmental toxicants results in serious brain abnormalities. Furthermore, heavy metals like lead, mercury, and cadmium can also disturb the normal levels of thyroid hormones in plasma. The thyroid disrupting potential of these heavy metals creates a negative impact on the cognitive performance of the brain. The heavy metals act either by inhibiting the carrier and enzymatic (Deiodinases) proteins of thyroid hormones or by altering the morphological features of the thyroid gland. The developing fetus is more prone to develop serious abnormal brain functions due to the exposure of these toxicants because early brain development is dependent upon thyroid hormones coming from mother. The main objective of this study is to explore the indirect effect of polychlorinated biphenyls and heavy metals on brain functions. In our country, many cases of brain abnormalities arise due to these environmental toxicants but the reality is ignored due to lack of proper information about this fact.</p> 2020-07-11T00:00:00-04:00 Copyright (c) 2020 Life Science Journal of Pakistan