Matricaria Chamomile Protective Effect Against Type-2 Diabetes Mellitus and Cancer Cell Linings

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Shahnai Basharat Syed Amir Gilani Faiza Iftikhar Muhammad Mustafa Qamar Mian Anjum Murtaza Sanabil Anmol Amna Imtiaz Sammana Ghazanfer Ameer Hamza Affifa Rajpoot

Abstract

Matricaria Chamomilla is one of the most popular old times herbal medicine which is known to mankind. This plant is a member of the Asteraceae family and is named by two common species, German and Roman kind. The dried flowers and extracts of chamomile plant contain many terpenoids and flavonoids including luteoline and epigenin which plays a vital role in protective effects against chronic diseases including Type-2 Diabetes Mellitus and Breast Cancer. Recent reports of 2015 have shown that prevalence of these two diseases has increased death rate globally as well as in Pakistan. Chamomile tea and other extracts containing its bioactive components (luteolin and epigenin) are used in many experimental studies for investigating their effect against diabetes and cancer cells. This review on inhibitory effects of chamomile plant in diabetes and cancer includes many latest researches, in which studies investigated human cells and rat cells. Subjects in the form of groups or individuals were given chamomile extracts to observe the effect on glycemic index in diabetes and induced apoptosis of cancer cells. It was viewed that chamomile extracts showed remarkable effect on glycemic index and induced apoptosis to inhibit cancer cells growth. These all studies were conducted in past 4 years and have detailed beneficial effects of chamomile as a herbal medicine. In this review chamomile’s origin, nutritional content, herbal properties and latest researches over inhibitory effects on diabetes and cancer cell growth are being highlighted.

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Reviews